21 days in Argentina: itinerary
A realistic 21-day route through Argentina with sensible stop lengths, travel days and costs.
6 min read · Updated 2026-08-01
Capital, wine country and southern Patagonia by domestic flights.
The route
- Days 1–5: Buenos Aires
- Days 6–10: Mendoza
- Days 11–15: El Calafate
- Days 16–20: El Chaltén
Why this order works
It keeps transfers short and ends near a major airport. Domestic flights are close to essential between regions — Buenos Aires to Patagonia or the north is a multi-day drive otherwise
What it costs
At mid-range pace, an estimated $2,310 per person on the ground, excluding flights.
When to run it
Best months: October, November, March, April, December.
Recommended destinations
Where to go in Argentina

Buenos Aires
Café culture, steak, tango and famously late nights across distinct neighbourhoods.
Explore Buenos Aires
Mendoza
Malbec vineyards on high desert plains beneath the Andes, with rafting and Aconcagua nearby.
Explore Mendoza
Bariloche
Northern Patagonian lake district: forests, lake drives in summer and skiing in winter.
Explore BarilocheEl Calafate
Base for the Perito Moreno glacier and the southern Patagonian ice field.
Explore El CalafateRelated guides
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